Why the study?
Does high on-treatment platelet reactivity predict early recurrence of ischemic events in patients with minor ischemic stroke or high-risk TIA treated with aspirin and clopidogrel?
Population
278 patients with minor ischemic stroke or high-risk TIA
Comparison
High on-treatment platelet reactivity assessed… vs Normal on-treatment platelet reactivity (NTPR)
Design
Cohort
Follow-up
3 months
Authors
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Identifies a high-risk subgroup on standard dual antiplatelet therapy;.
Does high on-treatment platelet reactivity predict early recurrence of ischemic events in patients with minor ischemic stroke or high-risk TIA treated with aspirin and clopidogrel?
In patients with minor stroke or TIA on dual antiplatelet therapy, high on-treatment platelet reactivity is independently associated with a more than 3-fold increased risk of early recurrent ischemic events.
Rao et al. (2017) studied this question.
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