Decreased Diastolic Ventricular Kinetic Energy in Young Patients with Fontan Circulation Demonstrated by Four-Dimensional Cardiac Magnetic Resonance Imaging
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Why the study?
Does 4D flow MRI demonstrate altered intraventricular kinetic energy in patients with Fontan circulation compared to healthy controls?
Population
11 patients with Fontan circulation and 8 healthy volunteers.
Comparison
Four-dimensional phase-contrast cardiac magnetic… vs Healthy volunteers.
Design
Cross-sectional
Authors
Discussion
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Implication
May indicate impaired diastolic filling in Fontan patients; leaves open whether 4D flow metrics predict outcomes or guide therapy.
Structured PICO
Does 4D flow MRI demonstrate altered intraventricular kinetic energy in patients with Fontan circulation compared to healthy controls?
P
Population
11 patients with Fontan circulation (median age 12 years, range 3-29) and 8 healthy volunteers (median age 26 years, range 23-36).
I
Intervention
Four-dimensional (4D) phase-contrast cardiac magnetic resonance imaging (MRI) to quantify intraventricular kinetic energy (KE).
C
Comparator
Healthy volunteers.
O
Outcome
Intraventricular kinetic energy (KE) indexed to stroke volume (SV) throughout the cardiac cycle.surrogate
Patients with Fontan circulation exhibit decreased diastolic ventricular kinetic energy compared to healthy controls, which may reflect impaired ventricular filling.
Limitations
- Small study population limiting statistical comparisons of subgroups
- Five out of eleven patients were ventilated during the examination
- Lack of age-matched controls
Cite This Study
Sjöberg et al. (2017) studied this question.
Topics
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