Why the study?
What is the contribution of prostanoids and cutaneous C fibers to basal cutaneous blood flow and ACh-mediated vasodilation in the forearm?
Population
Subjects undergoing forearm cutaneous microcirculation assessment
Comparison
Oral acetylsalicylic acid at doses of 81, 648… vs Baseline or unblocked state
Design
Other
Authors
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Prostanoids mediate axon reflex but not basal CuBF or ACh vasodilation; leaves open their role in other contexts or populations.
What is the contribution of prostanoids and cutaneous C fibers to basal cutaneous blood flow and ACh-mediated vasodilation in the forearm?
Prostanoids mediate the ACh-provoked axon reflex but do not significantly contribute to basal cutaneous blood flow or endothelium-dependent vasodilation in the forearm microcirculation.
Berghoff et al. (2002) studied this question.
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