Population
Precontracted porcine coronary artery (PCA) rings
Comparison
Bradykinin and arachidonic acid in the presence… vs Responses under different precontractile agents…
Design
Preclinical
Authors
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Identifies a novel bradykinin pathway in porcine coronaries; leaves open its relevance to human vessels or therapy.
This preclinical study demonstrates that bradykinin-induced relaxation in porcine coronary arteries involves a non-nitric oxide, arachidonic acid-mediated pathway independent of major known metabolic enzymes.
Weintraub et al. (1994) studied this question.
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