December 1, 1985The Journal of PhysiologyOpen Access

Single‐channel analysis of fast transient potassium currents from rat nodose neurones.

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Population

Cultured sensory neurones from rat nodose ganglia

Design

Preclinical

Authors

ECE. CooperUniversidade Estadual do Oeste do Paraná ASAlvin ShrierMcGill University

Discussion

Member takes

Implication

Caution against clinical extrapolation from rodent neurons; extends single-channel characterization of transient K+ currents.

Structured PICO

Population

Cultured sensory neurones from rat nodose ganglia

Intervention

Patch-clamp techniques to record single channels underlying the fast transient potassium current (IA)

Outcome

Single-channel conductance, kinetics, inactivation time constant, and mean channel open timesurrogate

This study characterizes the single-channel properties of fast transient potassium currents in rat nodose neurones, demonstrating a conductance of ~22 pS and voltage-dependent mean open times.

Cite This Study

Cooper et al. (1985) studied this question.

synapsesocial.com/papers/6a80fb9eda9cafc35e337cb0 https://doi.org/10.1113/jphysiol.1985.sp015896

View Full Paper

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Bookmark

Single‐channel analysis of fast transient potassium currents from rat nodose neurones.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Single‐channel analysis of fast transient potassium currents from rat nodose neurones.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider