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December 28, 2019Family MedicineOpen Access

Structural and Functional Changes in Coronary Vessels in Patients with Coronary Heart Disease in Combination with Type 2 Diabetes

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Why the study?

Cardiovascular complications drive morbidity and mortality in type 2 diabetes, with CHD manifesting 2-3 times more often than in individuals without diabetes.

Does the presence of type 2 diabetes mellitus worsen coronary artery disease severity and calcinosis in patients with stable angina pectoris?

Population

100 patients with coronary heart disease (stable angina pectoris)

Comparison

CHD with type 2 diabetes vs CHD without carbohydrate metabolism disorders

Authors

ВКВ. І. КошляАПА. В. Піскун

Discussion

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Member takes

Overview

Should not yet change imaging protocols in T2DM with stable angina; leaves open whether MSCT calcium scoring independently predicts events.

Structured PICO

Does the presence of type 2 diabetes mellitus worsen coronary artery disease severity and calcinosis in patients with stable angina pectoris?

P
Population
100 patients with coronary heart disease (stable angina pectoris), including 60 with concomitant type 2 diabetes and 40 without carbohydrate metabolism disorders (stable angina pectoris II-III FK).
I
Intervention
Presence of type 2 diabetes mellitus
C
Comparator
Absence of carbohydrate metabolism disorders
O
Outcome
Features of coronary artery disease and coronary artery calcinosis (total calcium index) assessed by non-invasive CT angiographysurrogate

Type 2 diabetes is associated with more severe, diffuse, and multi-vessel coronary atherosclerosis and early calcinosis in patients with stable angina.

Cite This Study

Кошля et al. (2019) studied this question.

synapsesocial.com/papers/6a811be0e6814737203bfdfahttps://doi.org/10.30841/2307-5112.5-6.2019.194274
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Coronary Calcification in Long-term Type 1 Diabetic Patients - A Study with Multi Slice Spiral Computed Tomography2004 · 18 citations
  2. 2Cohort prospective study of the heart and vessel condition in patients with ischemic heart disease combined with type 2 diabetes2019
  3. 3The frequency of coronary artery atherosclerotic plaques in patients with newly diagnosed type 2 diabetes mellitus2024
  4. 4Laboratory parameters associated with elevated coronary artery calcium burden in patients with newly diagnosed type 2 diabetes mellitus2024
  5. 5Сlinical and hemodynamic characteristics and coronary blood flow in patients with chronic coronary artery disease and type 2 diabetes2021 · 4 citations