Why the study?
Does the presence of type 2 diabetes mellitus and specific dyslipidemias worsen coronary artery lesions in patients with coronary artery disease?
Does the presence of type 2 diabetes mellitus and specific dyslipidemias worsen coronary artery lesions in patients with coronary artery disease?
Type 2 diabetes mellitus and atherogenic dyslipidemias (types IIb and IV) are associated with more severe, multivascular diffuse coronary artery lesions in patients with CAD.
The condition of coronary arteries in patients with coronary heart disease and diabetes mellitus type 2 depending on the types of dyslipidemias has been evaluated in the article. The study involved 105 patients with CAD who were treated in the cardiology Department of the Municipal Healthcare Institution Kharkiv city clinical hospital № 27. The main group consisted of 75 patients with CAD and diabetes mellitus type 2. The comparison group consisted of 30 patients with CAD without concomitant diabetes mellitus type 2. The control group consisted of 30 practically healthy people. In order to verify the diagnosis a multidetector (64-slice) CT angiography of the coronary arteries was conducted to all patients. The features of coronary lesions in patients CAD depending on the presence of diabetes mellitus type 2 were analyzed. The obtained data on the nature of coronary lesions in CAD patients with concomitant diabetes mellitus type 2 indicates unfavorable course of the atherosclerotic process against the background of diabetes mellitus type 2. In the group of patients with CAD and diabetes mellitus type 2 multivascular diffuse lesions of the coronary arteries occurred and the right branch of the left coronary artery hurt much more frequently by 33,13 %, the right coronary artery – by 28,39 %, the left branch of the coronary artery – by 15,37 %, the left envelope artery – by 22,77 %, the left anterior descending artery – by 13,27 %, respectively, compared with patients with CAD without diabetes. In patients with coronary artery disease and diabetes mellitus type 2 multivascular coronary lesions are more frequent with IIb and type IV dyslipidemia, that suggests a more adverse atherogenic impact of these types of dyslipidemias on the degree of coronary vessels damage
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Sypalo et al. (2017) studied this question.
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