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August 2, 2019ScienceRise Medical ScienceOpen Access

Cohort prospective study of the heart and vessel condition in patients with ischemic heart disease combined with type 2 diabetes

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Why the study?

The study aimed to evaluate the peculiarities of cardiac hemodynamics in patients with type 2 diabetes combined with ischemic heart disease and to identify correlations with other cardiovascular risk factors.

Does the presence of type 2 diabetes mellitus in patients with ischemic heart disease worsen cardiac remodeling, autonomic function, and carotid atherosclerosis compared to ischemic heart disease alone?

Population

100 patients with ischemic heart disease

Comparison

Concomitant type 2 diabetes (n=60) vs without carbohydrate metabolism violations (n=40)

Design

Cohort prospective study

Authors

ВКВ. І. КошляAPA. V. Piskun

Discussion

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Overview

Should not yet change practice; leaves open whether these hemodynamic and carotid patterns independently predict events in T2DM with IHD.

Structured PICO

Does the presence of type 2 diabetes mellitus in patients with ischemic heart disease worsen cardiac remodeling, autonomic function, and carotid atherosclerosis compared to ischemic heart disease alone?

P
Population
100 patients with ischemic heart disease (stable angina pectoris II-III FC), including 60 with concomitant type 2 diabetes mellitus and 40 without carbohydrate metabolism disorders, plus 30 healthy controls. Median age 55-57 years, predominantly female.
C
Comparator
Patients with ischemic heart disease without type 2 diabetes mellitus
O
Outcome
Cardiac hemodynamics, structural and functional changes of the common carotid artery (intima-media thickness), and presence of diabetic autonomic cardiac neuropathy and painless myocardial ischemiasurrogate

The presence of type 2 diabetes in patients with ischemic heart disease is associated with more pronounced left ventricular remodeling, autonomic neuropathy, and increased carotid intima-media thickness.

Limitations

  • Lack of coronary angiography to verify coronary atherosclerosis (relied on clinical diagnosis and MSCT)

Cite This Study

Кошля et al. (2019) studied this question.

synapsesocial.com/papers/6a811be0e6814737203bfdfbhttps://doi.org/10.15587/2519-4798.2019.174492
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Assessment of structural and functional myocardial characteristics in patients with chronic coronary artery disease and various glycemic status2021 · 2 citations
  2. 2Сlinical and hemodynamic characteristics and coronary blood flow in patients with chronic coronary artery disease and type 2 diabetes2021 · 4 citations
  3. 3Structural and Functional Changes in Coronary Vessels in Patients with Coronary Heart Disease in Combination with Type 2 Diabetes2019
  4. 4Clinical and instrumental characteristics of coronary heart disease in association with type 2 diabetes mellitus2024
  5. 5Structural and functional changes in the myocardium in chronic coronary syndrome and type 2 diabetes mellitus depending on the number of affected coronary arteries2026