Why the study?
Is variation in the APOH gene associated with measures of lipid metabolism in different racial groups?
Is variation in the APOH gene associated with measures of lipid metabolism in different racial groups?
Genetic variations in the APOH gene, particularly SNP 14917 (Cys306Gly), are associated with lipid metabolism traits such as triglyceride and apoE levels across different racial groups.
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APOH variant associations with lipid traits in Mexican Americans are hypothesis-generating; larger multi-ethnic studies needed before clinical consideration.
Leduc et al. (2008) studied this question.
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