Why the study?
Does timolol improve puerperal hypertension compared to methyldopa in patients with puerperal hypertension?
Does timolol improve puerperal hypertension compared to methyldopa in patients with puerperal hypertension?
Supports timolol as equivalent alternative for short-term puerperal hypertension; confirms comparable efficacy to methyldopa in this RCT.
Summary. Treatment of puerperal hypertension (diastolic blood pressure 95–105 mm Hg) with methyldopa 750–3000 mg/day was compared with treatment with timolol 15–60 mg/day in a random trial of 80 patients. Within these dose ranges and over the period studied (9 days) both drugs appeared equally effective. Therefore, in the treatment of puerperal hypertension, timolol could be considered as a suitable alternative to methyldopa.
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FTDLER et al. (1982) studied this question.
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