Why the study?
The association between remnant cholesterol and hypertension had not been explored in a large-scale Chinese population, and their temporal relationship required investigation.
Does high remnant cholesterol increase the risk of developing hypertension?
Population
2,199,366 individuals in a cross-sectional study and 24,252 individuals in a longitudinal study in China
Comparison
High remnant cholesterol vs lower levels or across lipid components
Design
Retrospective cross-sectional and longitudinal cohort study
Follow-up
At least a 3-year follow-up
Authors
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Remnant cholesterol may flag higher hypertension risk; hypothesis-generating for causality, requiring prospective trials before practice change.
Does high remnant cholesterol increase the risk of developing hypertension?
Remnant cholesterol levels are strongly associated with both the prevalence and incidence of hypertension, with increases in remnant cholesterol preceding the development of hypertension.
Chen et al. (2022) studied this question.
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