Why the study?
Elevated LDL-C and remnant cholesterol associate with hypertension, but whether higher remnant cholesterol associates with hypertension beyond LDL-C in general US adults was unknown.
Is higher remnant cholesterol associated with an increased prevalence of hypertension beyond LDL-C levels in the general US adult population?
Population
10,842 adults from NHANES 1999-2018
Comparison
Higher vs lower remnant cholesterol levels and LDL-C/RC concordant vs discordant groups
Design
Cross-sectional survey analysis
Authors
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RC may refine hypertension risk assessment beyond LDL-C; hypothesis-generating and should not yet change practice.
Is higher remnant cholesterol associated with an increased prevalence of hypertension beyond LDL-C levels in the general US adult population?
Remnant cholesterol is independently associated with hypertension in US adults, even among those with low LDL-C, suggesting it may be a distinct metabolic target for cardiovascular risk reduction.
Liu et al. (2023) studied this question.
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