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Cross-sectional study demonstrates waist circumference and body roundness index correlate with vitamin D in cardiology patients, indicating sex-specific adiposity links.
Background: This study sought to determine the accuracy of several anthropometric parameters in association with serum vitamin D (Vit. D) Concentrations and to compare the novel indices with the ancient ones. Methods: A total of 947 patients referred to the cardiology clinic were evaluated through a cross-sectional study. Data on demographic information, anthropometric indices, and biochemical measurements were gathered using a checklist. Both the multivariable regression modeling and area under the receiver-operating characteristic (ROC) were employed for the analysis. Results: Considering novel indices, BRI (Body Roundness Index) showed the most powerful correlation with serum Vit. D levels among both genders. Among ancient indices, WC (Waist Circumference) had the strongest association in both men and women groups. Based on the confounding factors-adjusted model, the highest odds ratio (OR) for the presence of Vit. D deficiency belonged to WHtR (Waist to Height Ratio) in women (OR, 0.347 (0.171-0.704) , P=0.003) while none of the indices predicted Vit. D deficiency significantly among men. A Vit. D concentration of 4.55 ng/ml was found as a cutoff based on the metabolic syndrome status. Conclusion: The most powerful association with serum Vit. D levels was detected for BRI in both genders among newly developed indices. In addition, only WHtR predicted Vit. D deficiency independent of confounding factors among women.
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Ashraf et al. (2023) studied this question.
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