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January 15, 2000Molecular and Cellular BiologyOpen Access

An Antitumor Drug-Induced Topoisomerase Cleavage Complex Blocks a Bacteriophage T4 Replication Fork In Vivo

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Authors

GHGeorge HongDuke UniversityKKKenneth N. KreuzerDuke Medical Center

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Hong et al. (2000) studied this question.

synapsesocial.com/papers/6a816aeb2d95cd89dee18d8fhttps://doi.org/10.1128/mcb.20.2.594-603.2000
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1DNA topoisomerase-targeting antitumor drugs can be studied in yeast.1988 · 505 citations
  2. 2Bacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coli.1989 · 31 citations
  3. 3Replication Forks Pause at Yeast Centromeres1992 · 138 citations
  4. 4The Mechanism of Inhibition of Topoisomerase IV by Quinolone Antibacterials1998 · 164 citations