Why the study?
Primary cardiac angiosarcoma is rare, highly aggressive, and presents with nonspecific manifestations, making diagnosis complex and challenging.
Multimodality imaging is valuable in diagnosing rare and aggressive primary cardiac angiosarcomas, especially when echocardiography shows unexplained intra-cardiac thrombus and hemorrhagic effusion.
May aid diagnosis of aggressive cardiac angiosarcomas when echocardiography is inconclusive; extends limited case evidence but requires validation.
A primary cardiac angiosarcoma (PCA) is very rare, highly aggressive, and metastatic in nature. The manifestations are often nonspecific, and the overall prognosis is extremely poor. The diagnosis of PCA can be complex and remains challenging. The key for diagnosis is echocardiography, and multimodality imaging is a more advantageous modality. Here, we present a rare case of a 41-year-old man who was diagnosed with PCA with multiple lung and bone metastases using multimodal imaging technology. Our case emphasizes the value of multimodality imaging in diagnosing PCA and suggests that patients showing intra-cardiac thrombus and hemorrhagic effusion on echocardiography without a clear explanation should be further investigated or closely followed.
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Xu et al. (2021) studied this question.
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