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January 1, 1966Journal of Lipid ResearchOpen Access

Disc electrophoresis of rat plasma lipoproteins

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Population

Rat plasma and human serum

Comparison

Disc electrophoresis at polyacrylamide gel… vs Human serum

Design

Preclinical

Authors

KNK. A. NarayanGovernment Rajaji HospitalHCHoward L. CreininUniversity of Illinois Urbana-ChampaignFKFred A. KummerowCarle Foundation Hospital

Discussion

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Implication

Rat lipoprotein profiles differ from human; leaves open species-specific translation to clinical lipid management.

Structured PICO

P
Population
Rat plasma and human serum
I
Intervention
Disc electrophoresis at polyacrylamide gel concentrations of 7.5, 5, and 3.75% after prestaining with Sudan black B
C
Comparator
Human serum (for comparison of electrophoretic patterns)
O
Outcome
Resolution and identification of lipoprotein componentssurrogate

Disc electrophoresis effectively separates rat plasma lipoproteins, revealing that rat low-density lipoproteins are smaller than human ones.

Cite This Study

Narayan et al. (1966) studied this question.

synapsesocial.com/papers/6a816f589e5e8e4efb4d59fbhttps://doi.org/10.1016/s0022-2275(20)39598-5
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1FURTHER CHARACTERIZATION OF THE HUMAN SERUM D 1.063-1.21, α1-LIPOPROTEIN*1962 · 83 citations
  2. 2DISC ELECTROPHORESIS‐I BACKGROUND AND THEORY*1964 · 4,574 citations
  3. 3DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*1964 · 18,953 citations