Population
1 child (3-year-old boy) with agammaglobulinemia and paralytic poliomyelitis
Design
Case_report
Follow-up
684 days after onset of illness
Authors
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Indicates risk of vaccine-derived poliomyelitis in immunocompromised hosts; leaves open need for targeted surveillance and vaccination strategies.
The Sabin poliovaccine can undergo antigenic variation during long-term multiplication in the intestinal tract of immunocompromised patients, leading to paralytic poliomyelitis.
Hara et al. (1981) studied this question.
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