Ecg Compared With Myocardial Ultrastructure in Anoxic Foetuses of Normal and Hyperglycaemic Rabbits

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Why the study?

Does maternal hyperglycemia delay ECG and myocardial ultrastructural changes in anoxic rabbit foetuses?

Structured PICO

Does maternal hyperglycemia delay ECG and myocardial ultrastructural changes in anoxic rabbit foetuses?

Population

4 pregnant rabbit mothers on the 29th day of pregnancy and their foetuses

Intervention

120 ml of 30% glucose solution intravenously on the 29th day of pregnancy (maternal hyperglycemia)

Comparator

Control rabbits (no glucose infusion)

Outcome

Correlation between ECG and ultrastructural state of myocardial cells in anoxic foetusessurrogate

Maternal hyperglycemia delayed the onset of pathological ECG and myocardial ultrastructural changes in anoxic rabbit foetuses compared to controls.

No takes yet. Share an insight, caveat, or question.

Hypothesis-generating for hyperglycemia delaying fetal anoxic injury; should not change human perinatal practice.

Gelli et al. (1968) studied this question.

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