Why the study?
Does amiodarone compared to metoprolol improve the treatment of new-onset atrial fibrillation after coronary artery bypass grafting?
Does amiodarone compared to metoprolol improve the treatment of new-onset atrial fibrillation after coronary artery bypass grafting?
In patients with new-onset atrial fibrillation after coronary artery bypass grafting, metoprolol appears more effective than amiodarone.
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Positions metoprolol as the preferred first-line agent for new-onset postoperative AF after.
INTRODUCTION: Atrial fibrillation (AF) is the most common arrhythmia affecting patients in open heart ICU after coronary artery bypass grafting (CABG). Most cardiac surgery textbooks recommend beta blockers as the drug of choice for treating such a condition while many experienced physicians and a number of anesthesiology references offer amiodarone as the drug of choice. Therefore, because of insufficient evidence and the aforementioned controversy, we decided to conduct a study evaluating these two antiarrhythmic medicines. METHODS: This is a double-blind, randomized, clinical trial performed on patients admitted for CABG at Amir al Momenin hospital in Arak province, Iran, who developed new onset AF after surgery. Based on the type of medication used, these patients were randomly divided into two groups: amiodarone (A) group and metoprolol (M) group. Each group consisted of 73 cases. All data were analyzed via SPSS 19. CONCLUSION: -value = 0.004).
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Kamali et al. (2017) studied this question.
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