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August 16, 2026Nuclear Medicine Communications

Diagnostic significance of ilioinguinal nodal uptake percentages in lower limb lymphoscintigraphy

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Authors

EGErkan Güler

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Overview

Retrospective study demonstrates varying ilioinguinal nodal uptake across lymphatic dysfunction stages in lower limb lymphoscintigraphy, suggesting quantitative thresholds aid visual diagnosis.

Key Points

  • Investigate the diagnostic significance and baseline distribution of ilioinguinal nodal uptake percentages in lower limb lymphoscintigraphy.
  • Retrospectively analyzed lymphoscintigraphy scans from 161 patients.
  • Calculated lower limb ilioinguinal nodal uptake percentages using baseline injection-site and 120-minute whole-body region-of-interest counts adjusted for count duration and radioactive decay.
  • Compared nodal uptake percentages between normal and abnormal limbs and across study-specific lymphoscintigraphic classification groups.
  • Median ilioinguinal nodal uptake was 18.6% (interquartile range: 11–27%) across 127 limbs displaying normal lymphoscintigraphic patterns.
  • Uptake was elevated in limbs with increased lymphatic flow reserve but decreased significantly with progressive lymphatic dysfunction (P < 0.001), differing across classification groups (P < 0.001).
  • Visual and semiquantitative assessments of bilateral ilioinguinal lymph node asymmetry demonstrated a moderate positive correlation (Pearson's r = 0.52, P < 0.001).

Cite This Study

Erkan Güler (2026) studied this question.

synapsesocial.com/papers/6a81799af2fb91fc834acc2ahttps://doi.org/10.1097/mnm.0000000000002233
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