Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 16, 2026Journal of Clinical Laboratory AnalysisOpen Access

Pediatric Systemic Lupus Erythematosus Complicated by Acute EBV and CMV Co‐infection

View Full Paper
Ask AI
Bookmark
Share

Authors

ACAnning ChenGJGengchun JiZLZiping Lan

Discussion

Loading...

Member takes

Implication

Case report demonstrates clinical recovery following antiviral and immunosuppressive therapy in pediatric systemic lupus erythematosus with acute EBV and CMV co-infection, highlighting potential...

Key Points

  • To describe the clinical presentation, suspected viral pathogenesis, and therapeutic management of pediatric systemic lupus erythematosus presenting alongside concurrent acute Epstein-Barr virus and cytomegalovirus infections.
  • Evaluated a 10-year-old female presenting with malar rash, fever, and arthritis through clinical examination, autoantibody panels, and viral serological assays.
  • Administered a combined treatment regimen consisting of intravenous methylprednisolone, belimumab, and oral ganciclovir, followed by serial clinical and laboratory monitoring.
  • Achieved clinical resolution of the malar rash and restored normal joint mobility following combined immunosuppressive and antiviral therapy.
  • Observed near-complete normalization of elevated inflammatory markers and circulating autoantibody titers at clinical follow-up.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a8179eff2fb91fc834ad747https://doi.org/10.1002/jcla.70330
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Juvenile lupus, cytomegalovirus infection and cardiac tamponade: case report2021 · 1 citations
  2. 2EBNA-1 antibody and autoimmune rheumatic diseases: A Mendelian Randomization Study2024 · 1 citations
  3. 3Exploring the Association between Epstein-Barr Virus and Systemic Lupus Erythematosus: Insights into Viral Triggers2025 · 1 citations
  4. 4Infections and Systemic Lupus Erythematosus: Binding or Sparring Partners?2015 · 72 citations
  5. 5A New Case of Paediatric Systemic Lupus Erythematosus with Onset after SARS-CoV-2 and Epstein-Barr Infection—A Case Report and Literature Review2024 · 12 citations