What question did this study set out to answer?

To optimize ultrasound-assisted extraction parameters for isolating bioactive compounds from Codonopsis javanica tubers and evaluate their in vitro antioxidant properties.

August 16, 2026Canadian Journal of Chemistry

Enhancing bioactive recovery from Codonopsis javanica tuber via ultrasound-assisted extraction: effects of extraction parameters and antioxidant evaluation

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LTLu Thi Mong ThyIndustrial University of Ho Chi Minh City NPNguyen Tan PhatIndustrial University of Ho Chi Minh City PHPham Thien HuongIndustrial University of Ho Chi Minh City

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Overview

Experimental study reveals optimized ultrasound-assisted extraction parameters for bioactive recovery from Codonopsis javanica tubers, indicating high antioxidant and pharmaceutical potential.

Key Points

To optimize ultrasound-assisted extraction parameters for isolating bioactive compounds from Codonopsis javanica tubers and evaluate their in vitro antioxidant properties.
Ultrasound-assisted extraction was performed on Codonopsis javanica tubers using ethanol, systematically testing solid-to-solvent ratios, extraction times, and temperatures.
Bioactive profiles (saponins, polyphenols, flavonoids, proteins, reducing sugars, and polysaccharides) were quantified, and antioxidant capacities were measured using DPPH and ABTS radical-scavenging assays.
Optimal extraction conditions (1:40 solid-to-solvent ratio, 45 min, 50 °C, 4 cycles) yielded saponins at 32.7 ± 2.5 mg/g, polysaccharides at 907.4 ± 2.5 mg/g, reducing sugars at 122.6 ± 0.2 mg/g, proteins at 38.78 ± 0.085 mg/g, polyphenols at 6.14 ± 0.045 mg GAE/g, and flavonoids at 1.906 ± 0.006 mg/g.
The optimized tuber extract exhibited potent antioxidant activity, with IC50 values of 40.34 µg/mL for DPPH and 228.39 µg/mL for ABTS.

Cite This Study

Thy et al. (2026) studied this question.

synapsesocial.com/papers/6a817a11f2fb91fc834ad9ae https://doi.org/10.1139/cjc-2026-0010

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August 16, 2026Canadian Journal of Chemistry

Enhancing bioactive recovery from Codonopsis javanica tuber via ultrasound-assisted extraction: effects of extraction parameters and antioxidant evaluation

View Full Paper

Ask AI

Bookmark

Authors

LTLu Thi Mong ThyIndustrial University of Ho Chi Minh City NPNguyen Tan PhatIndustrial University of Ho Chi Minh City PHPham Thien HuongIndustrial University of Ho Chi Minh City

Discussion

Member takes

Overview

Experimental study reveals optimized ultrasound-assisted extraction parameters for bioactive recovery from Codonopsis javanica tubers, indicating high antioxidant and pharmaceutical potential.

Key Points

To optimize ultrasound-assisted extraction parameters for isolating bioactive compounds from Codonopsis javanica tubers and evaluate their in vitro antioxidant properties.
Ultrasound-assisted extraction was performed on Codonopsis javanica tubers using ethanol, systematically testing solid-to-solvent ratios, extraction times, and temperatures.
Bioactive profiles (saponins, polyphenols, flavonoids, proteins, reducing sugars, and polysaccharides) were quantified, and antioxidant capacities were measured using DPPH and ABTS radical-scavenging assays.
Optimal extraction conditions (1:40 solid-to-solvent ratio, 45 min, 50 °C, 4 cycles) yielded saponins at 32.7 ± 2.5 mg/g, polysaccharides at 907.4 ± 2.5 mg/g, reducing sugars at 122.6 ± 0.2 mg/g, proteins at 38.78 ± 0.085 mg/g, polyphenols at 6.14 ± 0.045 mg GAE/g, and flavonoids at 1.906 ± 0.006 mg/g.
The optimized tuber extract exhibited potent antioxidant activity, with IC50 values of 40.34 µg/mL for DPPH and 228.39 µg/mL for ABTS.

Cite This Study

Thy et al. (2026) studied this question.

synapsesocial.com/papers/6a817a11f2fb91fc834ad9ae https://doi.org/10.1139/cjc-2026-0010

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