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Editorial
This 1954 editorial discusses the evolving understanding of cardiac edema pathogenesis, highlighting salt retention as a central mechanism.
Editorial1 August 1954SOME OBSERVATIONS ON THE PATHOGENESIS OF CARDIAC EDEMAH. J. L. MARRIOTTH. J. L. MARRIOTTSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-2-377 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEdema is a simple little word of humble Greek origin; and that is as far as edema walks with humility and simplicity. Its pathogenesis now presents one of the most complex problems in pathophysiology and many theories have already foundered in the uncharted sea of edema fluid. If among the complexities of today's concepts there is one trend towards simplification, it is that attention is now focused on one central mechanism, salt retention, as thefons et origoof most types of edema; whereas a decade or so ago it was customary to ascribe different mechanisms to different types of...1 PaineSmith RJR: The mechanism of heart failure, Am. J. Med. 6: 84, 1949. CrossrefMedlineGoogle Scholar2 Merrill AJ: Mechanisms of salt and water retention in heart failure, Am. J. Med. 6: 357, 1949. CrossrefMedlineGoogle Scholar3 BradleyBlake SEWD: Pathogenesis of renal dysfunction during congestive heart failure, Am. J. Med. 6: 470, 1949. CrossrefMedlineGoogle Scholar4 McMichael J: Cardiac venous congestion. Its causes and consequences, Am. J. Med. 6: 651, 1949. CrossrefMedlineGoogle Scholar5 Richards DW: Dynamics of congestive heart failure, Am. J. Med. 6: 772, 1949. CrossrefMedlineGoogle Scholar6 Starr I: Our changing viewpoint about congestive failure, Ann. Int. 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MARRIOTT PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRevisiting the cardio‐renal hypothesis: the pivotal role of the kidney in congestive heart failureNiere und HerzinsuffizienzDisorders of renal functionThe Role of Aldosterone in the Pathogenesis of Cardiac EdemaTHE MECHANISM OF FLUID RETENTION IN HEART FAILUREEtiology of Pre-Eclampsia-Eclampsia 1 August 1954Volume 41, Issue 2Page: 377-385KeywordsEdemaPathogenesisSalts ePublished: 1 December 2008 Issue Published: 1 August 1954 PDF downloadLoading ...
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