March 1, 1992Journal of Veterinary Internal Medicine

Doxorubicin-lnduced Cardiotoxicosis Clinical Features in 32 Dogs

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Why the study?

Does doxorubicin cause cardiotoxicosis in dogs with malignancies?

Population

175 dogs with various malignancies

Design

Preclinical

Authors

GMGlenna E. MauldinUniversity of Calgary PFPhilip R. FoxLouisiana State University APAmiya K. PatnaikHospital of the University of Pennsylvania

Discussion

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Implication

Doxorubicin may cause cardiotoxicity and fatal heart failure in dogs; leaves open optimal dosing and monitoring in veterinary oncology.

Structured PICO

Does doxorubicin cause cardiotoxicosis in dogs with malignancies?

Population

175 dogs with various malignancies

Intervention

Doxorubicin

Outcome

Clinical cardiac abnormalities (including electrocardiographic abnormalities and congestive heart failure)safety

Doxorubicin causes cardiotoxicosis in dogs, including fatal congestive heart failure, though therapeutic benefits may outweigh risks in most cases.

Cite This Study

Mauldin et al. (1992) studied this question.

synapsesocial.com/papers/6a81878db3060df1303bfa5a https://doi.org/10.1111/j.1939-1676.1992.tb03156.x

Topics

Heart failure HFrEF treatment

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Doxorubicin-lnduced Cardiotoxicosis Clinical Features in 32 Dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Doxorubicin-lnduced Cardiotoxicosis Clinical Features in 32 Dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider