Key result
Although 62 trials evaluated Huangqi injection for chronic heart failure, the methodological quality was too low to conduct a meta-analysis or draw definitive conclusions on its efficacy and safety.
Why the study?
Does Huangqi injection improve efficacy and safety in patients with chronic heart failure?
Population
Patients with chronic heart failure (CHF) from 62 RCTs and quasi-RCTs
Design
Systematic_review
Authors
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Insufficient evidence supports Huangqi injection in chronic heart failure; leaves open efficacy and safety pending rigorous RCTs.
Systematic Review (n=5,548)
Does Huangqi injection improve efficacy and safety in patients with chronic heart failure?
Current evidence is insufficient to draw conclusions on the efficacy and safety of Huangqi injection for chronic heart failure due to the low methodological quality of available trials.
Fu et al. (2011) conducted a systematic review in Chronic heart failure (n=5,548). Huangqi injection vs. Routine treatments alone was evaluated on Improvement of at least one class on the NYHA classification and Left Ventricular Ejection Fraction (LVEF). Although 62 trials evaluated Huangqi injection for chronic heart failure, the methodological quality was too low to conduct a meta-analysis or draw definitive conclusions on its efficacy and safety.
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