Key result
Baseline neutrophil-to-lymphocyte ratio independently predicted echocardiographic response to cardiac resynchronization therapy at 6 months (OR 1.506).
Why the study?
Does baseline neutrophil-to-lymphocyte ratio predict echocardiographic response to cardiac resynchronization therapy?
Population
70 consecutive patients undergoing cardiac resynchronization therapy (CRT), mean age 58 ± 13 years, 40 men.
Design
Cohort
Follow-up
6 months
Authors
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May inform CRT response prediction; hypothesis-generating and should not yet change practice.
Cohort (n=70)
No
Does baseline neutrophil-to-lymphocyte ratio predict echocardiographic response to cardiac resynchronization therapy?
Odds Ratio: 1.506 (95% CI 1.011–2.243)
p-value: p=0.035
Baseline neutrophil-to-lymphocyte ratio is an independent predictor of echocardiographic response to cardiac resynchronization therapy at 6 months.
Dilek Ural (2013) conducted a cohort in Heart failure (n=70). Baseline neutrophil-to-lymphocyte ratio was evaluated on Echocardiographic response to CRT (≥15% reduction in left ventricular end-systolic volume at 6 months) (OR 1.506, 95% CI 1.011-2.243, p=0.035). Baseline neutrophil-to-lymphocyte ratio independently predicted echocardiographic response to cardiac resynchronization therapy at 6 months (OR 1.506).
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