Key result
Anthropometric and atherogenic indices demonstrated strong relationships with fasting glucose, fasting insulin, and HOMA-IR in women with polycystic ovary syndrome.
Why the study?
PCOS contributes to endocrine and metabolic complications, and the study aimed to establish the usefulness of new anthropometric and atherogenic indices in evaluating metabolic disorders, particularly glucose and insulin abnormalities.
Do anthropometric and atherogenic indices correlate with glucose and insulin abnormalities in women with PCOS?
Cross-Sectional (n=49)
Do anthropometric and atherogenic indices correlate with glucose and insulin abnormalities in women with PCOS?
Anthropometric and atherogenic indices may be useful tools for evaluating glucose and insulin abnormalities in women with PCOS.
Indices may aid metabolic assessment in PCOS; hypothesis-generating, requires prospective validation before practice change.
Polycystic ovary syndrome (PCOS) contributes to endocrine and metabolic complications for women worldwide. The aim of this study was to establish the usefulness of new anthropometric indices and atherogenic indices in the evaluation of metabolic disorders, in particular, glucose and insulin abnormalities in the profiles of women with polycystic ovary syndrome (PCOS). In the study, a total of 49 women with PCOS aged between 18 and 39 years were recruited. All patients were tested for fasting glucose and insulin, lipid parameters, oral-glucose administration, and biochemical parameters. All of them underwent anthropometric measurements, such as BMI (body mass index), WHR (waist-to-hip ratio), WHtR (waist-to-height ratio), BAI (body adiposity index), VAI (visceral adiposity index), LAP (lipid accumulation product), BRI (body roundness index), ABSI (A body shape index), AIP (atherogenic risk of plasma), AC (atherogenic coefficient), Castelli risk index-I, Castelli risk index-II and (LCI) lipoprotein combine index, TG/HDL-C ratio, METS-IR (The metabolic score of insulin resistance), triglyceride glucose index (TyG index), triglyceride glucose-body mass index (TyG-BMI index) and triglyceride glucose-waist circumference index (TyG-WC index) were calculated. The analyzed anthropometric measurements/indices and atherogenic indices demonstrated significant correlations in PCOS women. T A strong relationship was found between fasting glucose, fasting insulin, glucose after 60 min, HOMA-IR index in the patients with PCOS. There was no significant relationship between HbA1c and other analyzed parameters and indices. Most of the analyzed anthropometric and atherogenic indices may be useful tools in evaluating metabolic disorders, and, in particular, glucose and insulin abnormalities in PCOS women.
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Jabczyk et al. (2023) conducted a cross-sectional in Polycystic ovary syndrome (n=49). Anthropometric and atherogenic indices was evaluated on Correlation between anthropometric/atherogenic indices and glucose/insulin abnormalities. Anthropometric and atherogenic indices demonstrated strong relationships with fasting glucose, fasting insulin, and HOMA-IR in women with polycystic ovary syndrome.
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