Key result
A modest reduction in dialysate sodium concentration was associated with a 4 mmHg reduction in pre- and post-dialysis mean arterial pressure (P<0.01 and P<0.001, respectively).
Why the study?
Does a reduction in dialysate sodium improve blood pressure control in haemodialysis patients?
Observational
Does a reduction in dialysate sodium improve blood pressure control in haemodialysis patients?
Mean Difference: -4
Absolute Event Rate: 97.1% vs 100.6%
p-value: p=<0.01
A modest reduction in dialysate sodium concentration in hemodialysis patients is associated with improved blood pressure control and reduced ultrafiltration requirements, particularly in older patients and women.
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Hypothesis-generating for lower dialysate sodium to aid BP control in hemodialysis; randomized trials needed before practice change.
Shah et al. (2012) conducted an observational in Haemodialysis. Reduction in dialysate sodium concentration vs. Baseline/higher dialysate sodium concentration was evaluated on Pre-dialysis mean arterial pressure (MAP) (4 mmHg reduction, p=<0.01). A modest reduction in dialysate sodium concentration was associated with a 4 mmHg reduction in pre- and post-dialysis mean arterial pressure (P<0.01 and P<0.001, respectively).
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