Hemodynamic and Humoral Effects of Low-Dose Aspirin in Treated and Untreated Essential Hypertensive Patients

30 patients with essential hypertension (10 with mild uncomplicated and untreated essential hypertension, 10 under chronic treatment with captopril 50 mg bid, and 10 under chronic treatment with atenolol 100 mg oid)

Aspirin 100 mg oid for one month

Corresponding placebo for one month

Blood pressure, heart rate, generated serum thromboxane B2, urinary excretion of thromboxane B2 and 6 keto prostaglandin F1 alpha, and plasma renin activity measured at the end of each one-month treatment periodsurrogate