Population
Trypanosomatids Crithidia fasciculata and Leptomonas seymouri
Comparison
Isolation and sequencing of U6 RNA genes vs Published Trypanosoma brucei U6 RNA sequence
Design
Preclinical
Authors
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May alter U6–5′ splice site pairing in trans-splicing; leaves open functional consequences across kinetoplastids.
The study identifies deviations in the conserved ACAGAG sequence of U6 RNA in C. fasciculata, suggesting a potential interaction between the 5' splice site region and U6 RNA in trans splicing.
Xu et al. (1994) studied this question.
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