Why the study?
Does high Lipoprotein(a) (≥30 mg/dL) increase the risk of all-cause death and acute coronary syndrome in patients after PCI who have achieved target lipid levels?
Population
411 Japanese patients who underwent percutaneous coronary intervention and achieved target lipid levels at…
Comparison
High serum Lipoprotein [Lp] levels ≥ 30 mg/dL vs Low serum Lipoprotein [Lp] levels < 30 mg/dL
Design
Cohort, Survival data and information about incident acute coronary syndrome…
Follow-up
median 4.7 years
Authors
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May inform residual risk stratification post-PCI despite achieved lipid targets; leaves open whether Lp(a) lowering improves outcomes.
Does high Lipoprotein(a) (≥30 mg/dL) increase the risk of all-cause death and acute coronary syndrome in patients after PCI who have achieved target lipid levels?
Elevated Lipoprotein(a) ≥30 mg/dL represents a significant residual risk factor for mortality and recurrent ACS in post-PCI patients, even when conventional lipid targets are achieved.
Konishi et al. (2014) studied this question.
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