Why the study?
There was no relevant review in the literature summarizing studies on the relationship between omentin-1 and CAD.
Decreased serum omentin-1 levels are an independent predictor of coronary artery disease and correlate with disease severity, suggesting its potential as a diagnostic and prognostic biomarker.
Omentin-1 may serve as a CAD biomarker; leaves open prospective validation before clinical use.
Like other adipokines, omentin-1 is secreted from visceral adipose tissue and plays a vital role in the development of chronic inflammatory diseases, including cardiovascular events. Recent studies have shown that circulating omentin-1 levels are associated with various metabolic risk factors, such as high blood pressure, increased waist circumference, dyslipidemia, and glucose intolerance. The decrease in serum omentin level is an independent predictor of Coronary Artery Disease (CAD) and is associated with the severity of this disease. Since there is no relevant review in the literature, we aimed to summarize the studies on the relationship between omentin-1 and CAD.
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Aşkın et al. (2020) studied this question.
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