Population
Smooth muscle fibers and regulatory components of myosin light chain phosphatase (CPI17 and MBS)
Design
Preclinical
Authors
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May implicate CPI17 in rapid smooth muscle tone regulation; hypothesis-generating for vascular therapies, with no practice change indicated.
The differential dephosphorylation kinetics of CPI17 and MBS suggest CPI17 regulates fast phosphorylation-dephosphorylation cycles in smooth muscle, while MBS does not.
Takizawa et al. (2002) studied this question.
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