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The utilization of indigenous plants for the treatment of various ailments has gained substantial attention due to their therapeutic benefits. The present study aimed to investigate the hepatoprotective and antioxidant potential of Ficus racemosa against ethanol induced liver damage in male Wistar albino rats. In the present study, Group I served as Control. Ethanol is orally administered to Group II rats, which resulted in significant decrease in the levels of antioxidant enzymes such as GST, GPx, SOD and CAT. These antioxidant enzymes play a pivotal role in combating oxidative stress. Elevated levels of lipid peroxidation were also observed in the serum and liver tissue after Ethanol administration by estimating the level of TBARS. Treatment with Ficus racemosa leaf extract (Group III) led to a substantial increase in the levels of antioxidant enzymes, when compared with ethanol induced untreated rats. Silymarin is used as a standard reference drug which was administered to Ethanol induced Group IV rats. The results revealed that, the administration of Ficus racemosa extract possibly mitigate the damage caused by oxidative stress thus, suggesting its role as an excellent antioxidant in treating liver disorders.
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M Sendhilvadivu (2024) studied this question.
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