Population
Isolated glomeruli with attendant arteriolar attachments harvested from rat kidneys
Comparison
Bradykinin (10 M) with or without inhibitors or… vs Basal conditions
Design
Preclinical
Authors
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Hypothesis-generating for prostaglandin-independent bradykinin effects on renin in rat glomeruli; leaves open translation to human disease.
Bradykinin stimulates renin release from isolated rat glomeruli through a pathway that is at least partially independent of prostaglandin synthesis.
W. H. Beierwaltes (1987) studied this question.
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