Prednisone provided prompt and dramatic clinical and laboratory improvement in a patient with diffuse fasciitis with eosinophilia and polyarthritis.
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May support empiric prednisone in eosinophilic fasciitis with polyarthritis; hypothesis-generating case report requiring prospective trials.
Articular involvement has been infrequently reported in diffuse fasciitis with eosinophilia. We report a patient with diffuse fasciitis with eosinophilia, concurrent symmetrical polyarthritis, and bilateral carpal tunnel syndrome. Light microscopy and immunofluorescence studies of synovium and full-thickness calf biopsy were done. Synovial fluid analyses showed mildly inflammatory fluid. Response to prednisone, clinically and by laboratory indicators, was prompt and dramatic.
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Rosenthal et al. (1980) studied this question.
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