Why the study?
Do milrinone and OPC 3911 produce relaxant effects in isolated human mesenteric vessels?
Population
Isolated human mesenteric arteries and veins in vitro
Design
Preclinical
Authors
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May support PDE inhibitor testing in mesenteric vasorelaxation models; leaves open translation to human clinical settings.
Do milrinone and OPC 3911 produce relaxant effects in isolated human mesenteric vessels?
Milrinone and OPC 3911 demonstrate significant relaxant effects on isolated human mesenteric vessels, with OPC 3911 showing greater potency.
Lindgren et al. (1989) studied this question.
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