Why the study?
Do insulin-dependent diabetic patients have reduced 0.1 Hz microcirculatory fluctuations compared to healthy controls?
Population
46 human subjects, comprising 23 insulin-dependent diabetic patients and 23 age-matched controls.
Design
Case-control
Authors
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May indicate early autonomic dysfunction in diabetes; hypothesis-generating and requires prospective validation before clinical use.
Do insulin-dependent diabetic patients have reduced 0.1 Hz microcirculatory fluctuations compared to healthy controls?
Insulin-dependent diabetic patients exhibit a significant reduction in 0.1 Hz microcirculatory fluctuations, suggesting early sympathetic autonomic dysfunction.
Luciano Bernardi (1997) studied this question.
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