Why the study?
Does antihypertensive medication use during pregnancy increase the risk of cardiovascular malformations in infants?
Population
9,817 infants from 10 US states
Comparison
Antihypertensive medication treatment during… vs No antihypertensive medication treatment /…
Design
Case-control
Authors
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Supports fetal echocardiography consideration in exposed pregnancies; leaves open medication effects versus confounding by hypertension.
Does antihypertensive medication use during pregnancy increase the risk of cardiovascular malformations in infants?
Antihypertensive medication use during pregnancy, as well as underlying untreated hypertension, may increase the risk of specific left and right obstructive and septal defects in infants.
Caton et al. (2009) studied this question.
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