Prevalence and outcomes of atrial fibrillation in hospitalizations during pregnancy and puerperium

Figures

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  Figure 1. Selection flow ydiagram of target population. Selection flow diagram of target population. NIS, National Inpatient Sample.

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  Figure 2. Temporal trends of atrial fibrillation during pregnancy and puerperium. Temporal trend of pregnancy-related atrial fibrillation in the United States from 2008 through 2017. The rates of in-hospital prevalence among patients with atrial fibrillation increased (2.18 per 10,000 in 2008 vs. 4.87 per 10,000 in 2017; Ptrends < 0.001). Error bars represent the 95% confidence interval (95% CI) derived from Normal Approximation method.

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  Figure 3. The prevalence of atrial fibrillation increased with age. The prevalence of atrial fibrillation per 100,000 pregnancy-related hospitalizations increased with advancing maternal age. Error bars represents the 95% confidence interval (95% CI) derived from Normal Approximation method.

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  Figure 4. Temporal trends of atrial fibrillation in subgroups. (A) Subgroup analyses categorized by race. (B) Subgroup analyses categorized by household income. (C) Subgroup analyses categorized by old adult parturient. (D) Subgroup analyses categorized by age. (E) Subgroup analyses categorized by insurance type. (F) Subgroup analyses categorized by hospital region exhibited.

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  Figure 5. Prevalence of adverse events in different CHA2DS2-VASc stratification. The mortality rate of AF during pregnancy and puerperium was associated with an increasing CHA2DS2-VASc score (Ptrend < 0.001), which was 0.35% (95% CI: 0.24%–0.47%) in the low-risk group, 1.30% (95% CI: 0.98%–1.62%) in the moderate-risk group, and 2.18% (95% CI: 0.86%–3.51%) in the high-risk group. The prevalence of stroke, acute myocardial infarction, acute heart failure, and cardiac shock during pregnancy and puerperium was also significantly correlated with the increasing CHA2DS2-VASc score in AF patients (Ptrend < 0.001).