A novel method using magnetic nanoparticles sensitized with soluble PV receptor efficiently extracts poliovirus from stool extracts.
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May aid poliovirus surveillance via efficient stool extraction; leaves open clinical translation pending human validation.
A method for extracting poliovirus (PV) from stool extracts was developed. Magnetic nanoparticles sensitized with soluble PV receptor efficiently extracted PV pseudovirus (>99% extraction) or endogenous infectious PVs (>90% extraction) from stool extracts. This method would be useful for extraction of PV from crude biological samples.
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Minetaro Arita (2013) studied this question.
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