Why the study?
Does central hypervolemia induced by water immersion increase plasma ANP and urinary cGMP in healthy male subjects?
Population
5 healthy male subjects
Comparison
Central hypervolemia induced by water immersion… vs Control day without water immersion
Design
Other
Follow-up
3 hours of immersion and 1 hour postimmersion
Authors
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Supports ANP's role in natriuresis during hypervolemia; extends mechanistic insights but leaves open clinical applications.
Does central hypervolemia induced by water immersion increase plasma ANP and urinary cGMP in healthy male subjects?
Central hypervolemia induced by water immersion significantly increases plasma ANP and urinary cGMP, suggesting ANP contributes to the natriuretic and diuretic response.
Leung et al. (1987) studied this question.
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