Why the study?
Does elevated endogenous cortisol reduce autonomic neuroendocrine and symptom responses to subsequent hypoglycemia in healthy young adults?
Population
12 healthy young adults
Comparison
Infusions of a pharmacological dose of… vs Saline infusions on day 1
Design
Other
Follow-up
2 days
Authors
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May implicate cortisol in hypoglycemia-associated autonomic failure; leaves open whether targeting it alters risk in diabetes.
Does elevated endogenous cortisol reduce autonomic neuroendocrine and symptom responses to subsequent hypoglycemia in healthy young adults?
Increased endogenous cortisol secretion blunts autonomic and symptom responses to subsequent hypoglycemia, suggesting a mechanism for hypoglycemia-associated autonomic failure in diabetes.
McGregor et al. (2002) studied this question.
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