August 11, 2015PLoS ONEOpen Access

Prothrombin Time and Activated Partial Thromboplastin Time Testing: A Comparative Effectiveness Study in a Million-Patient Sample

View Full Paper

Ask AI

Bookmark

Why the study?

Are preoperative PT and aPTT tests frequently used unnecessarily in patients without evidence-based indications?

Population

1,053,472 consecutive patients admitted for elective surgery from 2009 to 2012 at 19 major teaching…

Design

Cohort

Authors

MCManu N. Capoor JSJerry StonemetzJohns Hopkins University JBJohn C. BairdUniversity of Idaho

Discussion

Member takes

Implication

High unnecessary preoperative coagulation testing suggests waste; leaves open whether targeted de-implementation reduces use without harm.

Structured PICO

Are preoperative PT and aPTT tests frequently used unnecessarily in patients without evidence-based indications?

Population

1,053,472 consecutive patients admitted for elective surgery from 2009 to 2012 at 19 major teaching hospitals and 8 hospital-affiliated surgical centers in 7 US states and the District of Columbia. A subset of 682,049 patients (64.7%) with available history and physical records were analyzed.

Intervention

Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT) testing

Outcome

Proportion of patients who received PT or aPTT tests who lacked evidence-based reasons for testing (unnecessary tests)

Routine preoperative PT and aPTT testing is highly prevalent and overwhelmingly unnecessary based on patient history and physical findings, representing significant healthcare waste.

Cite This Study

Capoor et al. (2015) studied this question.

synapsesocial.com/papers/6a82492aaedbb2834ec6aa08 https://doi.org/10.1371/journal.pone.0133317

View Full Paper

Ask AI

Bookmark

Implication

High unnecessary preoperative coagulation testing suggests waste; leaves open whether targeted de-implementation reduces use without harm.

Prothrombin Time and Activated Partial Thromboplastin Time Testing: A Comparative Effectiveness Study in a Million-Patient Sample

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Prothrombin Time and Activated Partial Thromboplastin Time Testing: A Comparative Effectiveness Study in a Million-Patient Sample

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider