Why the study?
Does control of anticoagulant therapy by activated partial thromboplastin time compared to one-stage prothrombin time affect the incidence of bleeding in patients on anticoagulant therapy?
Population
107 patients on anticoagulant therapy
Comparison
Control of anticoagulant therapy by activated… vs Control of anticoagulant therapy by one-stage…
Design
RCT, Randomized
Authors
Loading...
Either aPTT or PT may guide anticoagulation monitoring; confirms comparable bleeding safety in this RCT.
Does control of anticoagulant therapy by activated partial thromboplastin time compared to one-stage prothrombin time affect the incidence of bleeding in patients on anticoagulant therapy?
One-stage prothrombin time and activated partial thromboplastin time are comparable in terms of bleeding incidence for monitoring anticoagulant therapy, though prothrombin time may offer practical advantages.
Pearce et al. (1973) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: