Key result
Owren's Thrombotest used as a guide for anticoagulant therapy resulted in similar thromboembolic complications but less hemorrhage compared to Quick's test.
Why the study?
Does Owren's Thrombotest reduce thromboembolic complications and hemorrhage compared to Quick's one-stage prothrombin time in patients on long-term anticoagulant therapy?
Population
24 patients receiving either coumarin or phenindione derivatives as prophylaxis in cardiac or vascular disease
Comparison
Owren's Thrombotest used as a guide for… vs Quick's one-stage prothrombin time used as a…
Design
Cohort
Follow-up
1 year per period
Authors
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May support preferring Owren's Thrombotest to reduce hemorrhage; leaves open confirmation in randomized trials.
Observational (n=24)
Does Owren's Thrombotest reduce thromboembolic complications and hemorrhage compared to Quick's one-stage prothrombin time in patients on long-term anticoagulant therapy?
Owren's Thrombotest may be preferable to Quick's test for guiding long-term anticoagulant therapy due to a lower incidence of hemorrhage.
I. Myron Vigran (1961) conducted an observational in Cardiac or vascular disease (n=24). Owren's Thrombotest vs. Quick's one-stage prothrombin time was evaluated on Incidence of thromboembolic complications and hemorrhage. Owren's Thrombotest used as a guide for anticoagulant therapy resulted in similar thromboembolic complications but less hemorrhage compared to Quick's test.
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