Key result
Thrombotest yielded lower prothrombin times (0.5 to 0.67 of Quick-test times) and occasionally grossly inaccurate results compared to the modified Quick test.
Why the study?
Does the Thrombotest provide comparable and accurate prothrombin time measurements compared to the modified Quick test in patients on anticoagulant therapy?
Population
45 patients on anticoagulant therapy with prothrombinopenic drugs
Comparison
Thrombotest for measuring prothrombin time after… vs Modified Quick-test for measuring prothrombin time
Design
Cross-sectional
Authors
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Thrombotest may be unsuitable for reliable anticoagulation monitoring; leaves open standardization of prothrombin time assays.
Observational (n=45)
Does the Thrombotest provide comparable and accurate prothrombin time measurements compared to the modified Quick test in patients on anticoagulant therapy?
The Thrombotest is less accurate and yields lower prothrombin times compared to the modified Quick test, making it inadequate for managing hypoprothrombinemia.
Shoshkes et al. (1963) conducted an observational in Anticoagulant therapy with prothrombinopenic drugs (n=45). Thrombotest vs. Modified Quick Test was evaluated on Increase in prothrombin times. Thrombotest yielded lower prothrombin times (0.5 to 0.67 of Quick-test times) and occasionally grossly inaccurate results compared to the modified Quick test.
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