Why the study?
Are EDTA samples stable for prothrombin time measurement using the combined thromboplastin reagent?
Population
Blood samples for prothrombin time (PT) measurement
Comparison
EDTA samples tested with combined thromboplastin… vs Quick method and different tube materials
Authors
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EDTA tubes may avoid artifactual PT shortening from cold-activated factor VII; leaves open validation across reagents and lab conditions.
Are EDTA samples stable for prothrombin time measurement using the combined thromboplastin reagent?
EDTA samples are stable for PT measurement using the combined thromboplastin reagent, highlighting the importance of tube material in preventing artifactual factor VII activation.
Juha Horsti (2001) studied this question.
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