Why the study?
Does the presence of metabolic syndrome further worsen peripheral wave reflection and endothelial function in untreated essential hypertensive patients?
Does the presence of metabolic syndrome further worsen peripheral wave reflection and endothelial function in untreated essential hypertensive patients?
In untreated hypertensive patients, metabolic syndrome impairs central pulse wave velocity but does not further deteriorate peripheral wave reflection or conduit artery endothelial function beyond the effects of hypertension, age, and gender.
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Metabolic syndrome may not further impair wave reflection or endothelial function beyond hypertension; hypothesis-generating for differential stiffness effects.
Plantinga et al. (2008) studied this question.
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