Population
Encephalomyocarditis virus (EMC) infected L-cells and cell-free systems
Comparison
Endogenous or added EMC virus RNA vs Uninfected cells or cells 2-h post-infection
Design
Preclinical
Authors
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Indicates upregulated proteolytic processing in EMC-infected cells; leaves open mechanistic roles in viral myocarditis and requires in vivo validation.
The study demonstrates that during EMC virus infection, there is an increase in the activity of enzymes responsible for processing or cleaving the nascent virus-specific polypeptide chain.
Estéban et al. (1974) studied this question.
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